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Calcification of the leaflets of the aortic valve is a common with increasing age, but the mechanism is likely to be more related to increased lipoprotein deposits and inflammation than the "wear and tear" of advance age. [17] Aortic stenosis due to calcification of tricuspid aortic valve with age [16] comprises >50% of the
Bicuspid aortic valve (BAV) is a form of heart disease in which two of the leaflets of the aortic valve fuse during development in the womb resulting in a two-leaflet (bicuspid) valve instead of the normal three-leaflet (tricuspid) valve. BAV is the most common cause of heart disease present at birth and affects approximately 1.3% of adults. [2]
Common causes of aortic regurgitation include vasodilation of the aorta, previous rheumatic fever, infection such as infective endocarditis, degeneration of the aortic valve, and Marfan's syndrome. Aortic stenosis can also be caused by rheumatic fever and degenerative calcification . [ 7 ]
Regurgitation or leaky valve. Regurgitation occurs when a valve doesn’t close properly, leading blood to flow backward or leak into the heart chamber in between heart contractions. Atresia.
Aortic valve repair or aortic valve reconstruction describes the reconstruction of both form and function of the native and dysfunctioning aortic valve. Most frequently it is applied for the treatment of aortic regurgitation. It can also become necessary for the treatment of an aortic aneurysm, less frequently for congenital aortic stenosis. [53]
Aortic valve stenosis is the most common cause of LVOTO. Aortic valve stenosis means the aortic valve has narrowed and is not opening freely. The aortic valve opens to allow blood to flow from the left ventricle to the aorta. Stenosis here leads to a narrowing of the passage for blood to flow out of the left ventricle, thus a LVOTO.
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