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Buspirone also seems to have lower affinities for the serotonin 5-HT 2A, 5-HT 2B, 5-HT 2C, 5-HT 6, 5-HT 7 receptors where it probably acts as an antagonist. [ 37 ] In addition to binding to serotonin receptors, buspirone is an antagonist of the dopamine D 2 receptor with weak affinity.
The only exception to this rule is umespirone, which has a very long duration with a single dose lasting as long as 23 hours. [45] Unfortunately, umespirone has not been commercialized. Although never commercially produced, Bristol-Myers Squibb applied for a patent on October 28, 1993, and received the patent on July 11, 1995, for an extended ...
Special pages; Permanent link; Page information; Cite this page; Get shortened URL; Download QR code; ... Side effects of buspirone by incidence include: [1] [2] [3] [4]
Buspirone (Buspar) – 5-HT 1A receptor partial agonist; Lithium (Eskalith, Lithobid) – mood stabilizer (mechanism of action unknown/unclear) Thyroxine (T 4) – thyroid hormone (thyroid hormone receptor agonist) Triiodothyronine (T 3) – thyroid hormone (thyroid hormone receptor agonist)
Keppra (levetiracetam) – an anticonvulsant drug which is sometimes used as a mood stabilizer and has potential benefits for other psychiatric and neurologic conditions such as Tourette syndrome, anxiety disorder, and Alzheimer's disease; Klonopin – anti-anxiety and anti-epileptic medication of the benzodiazepine class
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Gepirone is indicated for the treatment of major depressive disorder (MDD) in adults. [1] Of 15 clinical trials of gepirone for major depressive disorder submitted to the U.S. Food and Drug Administration (FDA), three were excluded for methodological reasons, three were deemed "failed" and "uninformative", seven were deemed negative and did not demonstrate effectiveness, and two were deemed ...
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