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Solifenacin, sold as the brand name Vesicare [a] among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). [1] [2] It may help with incontinence, urinary frequency, and urinary urgency. [3] Benefits appear similar to other medications in the class. [4] It is taken by mouth. [1]
Intravesical drug delivery through a urinary catheter. Intravesical drug delivery is the delivery of medications directly into the bladder by urinary catheter.This method of drug delivery is used to directly target diseases of the bladder such as interstitial cystitis and bladder cancer, but currently faces obstacles such as low drug retention time due to washing out with urine and issues with ...
Zycosan, for horses, is a heparin-like compound and is the first injectable pentosan product to receive approval by the US Food and Drug Administration (FDA). [ 21 ] In December 2022, the US Food and Drug Administration (FDA) approved pentosan polysulfate (Zycosan) for the control of clinical signs associated with osteoarthritis in horses. [ 21 ]
The urine arrives in the pleural space either retroperitoneally (under the peritoneum), or via the retroperitoneal lymphatics. [8] Urine can reach the pleural space either directly or indirectly. It can reach directly, by going through pores in the thoracic diaphragm due to a pressure gradient, or by a rupture of a urinoma releasing the ...
"The longer the bladder is full, the greater the likelihood of leakage of urine," Dr. Fromer says. In the short-term, you might feel embarrassed that you "peed your pants" and need a swift outfit ...
If the retention is due to neurological damage, there is a disconnect between the brain to muscle communication, which can make it impossible to completely empty the bladder. [7] If the retention is due to muscle damage, it is likely that the muscles are not able to contract enough to completely empty the bladder. [7]
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