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Glycated hemoglobin (also called glycohemoglobin) is a form of hemoglobin (Hb) that is chemically linked to a sugar. ("Glycosylated haemoglobin" is a misnomer because glycation and glycosylation are different processes, of which only the former is relevant in this case.)
Measurement of HbA1c—the predominant form of glycated hemoglobin—enables medium-term blood sugar control to be monitored in diabetes. Some glycation products are implicated in many age-related chronic diseases, including cardiovascular diseases (the endothelium, fibrinogen, and collagen are damaged) and Alzheimer's disease (amyloid proteins ...
This method measures the level of glycated hemoglobin, which is representative of the average blood glucose levels over the last, approximately, 120 days. [ 36 ] In either case, the chemical system is commonly contained on a test strip which is inserted into a meter, and then has a blood sample applied.
For instance, some proteins do not fold correctly unless they are glycosylated. [2] In other cases, proteins are not stable unless they contain oligosaccharides linked at the amide nitrogen of certain asparagine residues. The influence of glycosylation on the folding and stability of glycoprotein is twofold. Firstly, the highly soluble glycans ...
1 Glycation vs. Glycosylation. 2 comments. 2 Merge. 1 comment. 3 Interpretation of HbA1c Results. 2 comments. 4 Etymology? 4 comments. 5 NDEP says the preferred term ...
Levels greater than 9% are associated with poor control of the glycated hemoglobin, and levels greater than 12% are associated with very poor control. Diabetics who keep their glycated hemoglobin levels close to 7% have a much better chance of avoiding the complications that may accompany diabetes (than those whose levels are 8% or higher). [88]
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Glycated hemoglobin (hemoglobin A1c or Hb A1c), a surrogate marker for blood glucose levels; A1C receptor, the alpha-1C adrenergic receptor; Transportation and vehicles