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In cancer cells, major changes in gene expression increase glucose uptake to support their rapid growth. Unlike normal cells, which produce lactate only when oxygen is low, cancer cells convert much of the glucose to lactate even in the presence of adequate oxygen. This is known as the “Warburg Effect.”
A newly identified colon cancer gene may drive the disease by making the environment in the vicinity of tumors more hospitable to them, researchers say. Why does colon cancer grow so fast? Study ...
Cancer cells, however, have the ability to grow without these external signals. There are multiple ways in which cancer cells can do this: by producing these signals themselves, known as autocrine signaling ; by permanently activating the signaling pathways that respond to these signals; or by destroying 'off switches' that prevents excessive ...
Cancer cells have unique features that make them "immortal" according to some researchers. The enzyme telomerase is used to extend the cancer cell's life span. While the telomeres of most cells shorten after each division, eventually causing the cell to die, telomerase extends the cell's telomeres. This is a major reason that cancer cells can ...
The findings raise hope for more effective treatments for pancreatic cancer, which has a poor survival rate. Shutdown of crucial gene helps world’s deadliest cancer grow rapidly – study Skip ...
The researchers found that the bladder cancer cells grew at a “much faster” rate in mice that had fewer Y chromosomes compared to those with many, according to the release.
The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis. DNA damage is considered to be the primary cause of cancer. [17] More than 60,000 new naturally-occurring instances of DNA damage arise, on average, per human cell, per day, due to endogenous cellular processes (see article DNA damage (naturally occurring)).
Some cancer treatments, like chemotherapy and radiation, can damage reproductive cells and organs. Doctors say fertility preservation should be discussed with all young people with cancer, who ...
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