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Ethylene glycol poisoning is poisoning caused by drinking ethylene glycol. [1] Early symptoms include intoxication, vomiting and abdominal pain. [1] Later symptoms may include a decreased level of consciousness, headache, and seizures. [1] Long term outcomes may include kidney failure and brain damage. [1]
Ethylene glycol, antifreeze, is extremely toxic to dogs. It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol.
Fomepizole is used to treat ethylene glycol and methanol poisoning. It acts to inhibit the breakdown of these toxins into their active toxic metabolites. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase, [6] found in the liver. This enzyme plays a key role in the metabolism of ethylene glycol, and of methanol.
The effect of ethanol on dogs and cats is similar to its effect on humans, also causing intoxication. Death is unlikely given supportive care (only one death is known). Ethanol is also an antidote for ethylene glycol poisoning. [47] Mouse and rat poison, anticoagulant type Rodenticide is commonly found in the house or garage.
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An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton) , "(medicine) given as a remedy".
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Plaintiffs sued Sterigenics and Sotera Health LLC over its use of ethylene oxide, a chemical said to cause cancer, according to the U.S. Environmental Protection Agency. The plant, located near ...