Search results
Results from the WOW.Com Content Network
aEF2/eEF2 found in most archaea and eukaryotes, including humans, contains a post translationally modified histidine diphthamide. [8] It is the target of diphtheria toxin (from Corynebacterium diphtheriae ), and exotoxin A (from Pseudomonas aeruginosa ). [ 9 ]
13631 Ensembl ENSG00000103319 ENSG00000284161 ENSMUSG00000035064 UniProt O00418 O08796 RefSeq (mRNA) NM_013302 NM_001267710 NM_001267711 NM_007908 RefSeq (protein) NP_037434 NP_001254639 NP_001254640 NP_031934 Location (UCSC) Chr 16: 22.21 – 22.29 Mb Chr 7: 120.44 – 120.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor-2 kinase (eEF-2 kinase or eEF ...
The steps in this microcycle are (1) positioning the correct aminoacyl-tRNA in the A site of the ribosome, which is brought into that site by eEF1, (2) forming the peptide bond, and (3) shifting the mRNA by one codon relative to the ribosome with the help of eEF2.
Eukaryotic elongation factor 2 (eEF2) is a regulateable GTP-dependent translocase that moves nascent polypeptide chains from the A-site to the P-site in the ribosome. Phosphorylation of threonine 56 is inhibitory to the binding of eEF2 to the ribosome. [11]
eIF2 is a heterotrimer of a total molar mass of 126 kDa that is composed of the three sub-units: α (sub-unit 1), β (sub-unit 2), and γ (sub-unit 3). The sequences of all three sub-units are highly conserved (pairwise amino acid identities for each sub-unit range from 47 to 72% when comparing the proteins of Homo sapiens and Saccharomyces cerevisiae).
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
ADP-ribose. ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis.
The 401(k) has been around for 46 years, and in that time, it has become the dominant workplace retirement plan employees of all ages use to save for their futures. Each generation has made its ...