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Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically in the treatment of pattern hair loss (androgenic alopecia or pattern baldness) in men and women.
It is used to control estrogen synthesis. [2] ATD was present in some over-the-counter bodybuilding supplements until 2009, as well as Topical ATD solutions that work transdermally. The product was developed and commercialized in the dietary supplement market place by industry journeyman Bruce Kneller, who holds a United States Patent for use ...
Plasma levels of DHEA in adult men are 10 to 25 nM, in premenopausal women are 5 to 30 nM, and in postmenopausal women are 2 to 20 nM. [25] Conversely, DHEA-S levels are an order of magnitude higher at 1–10 μM. [25] Levels of DHEA and DHEA-S decline to the lower nanomolar and micromolar ranges in men and women aged 60 to 80 years. [25]
The compound shows preferential affinity for the ERα over the ERβ. [ 2 ] [ 4 ] Although 17α-estradiol is far weaker than 17β-estradiol as an agonist of the nuclear estrogen receptors , it has been found to bind to and activate the brain -expressed ER-X with a greater potency than that of 17β-estradiol, suggesting that it may be the ...
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Atypical (dual estrogen and nitrogen mustard alkylating antineoplastic): Estramustine phosphate sodium (Emcyt) – 140 mg; Oral estradiol valerate (except in combination with dienogest as an oral contraceptive) is not available in the U.S. and is used primarily in Europe. [2]
Cost: $88 | Product type: Supplements | Key ingredients: Saw Palmetto, biotin, vitamins A, C, D; ashwagandha exomes, Irish moss peptides, pea sprout extract | Best for: Thinning and hair loss ...