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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
But if hitting the gym hard and lifting heavy, you're likely building lean muscle mass while dropping body fat. "Because muscle is more dense than fat, these two actions can offset each other on ...
The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [5]
The protein kinase domain is 330 amino acids long and is located near the N-terminus of the protein. [ 23 ] [ 24 ] In addition to its kinase domain, HIPK2 has two nuclear localization signals, [ 25 ] a SUMO interaction motif, [ 25 ] an auto-inhibitory domain [ 23 ] a transcriptional co-repression domain, [ 13 ] and several interaction domains ...
If you want to really overachieve, instead of creamy dressing, you can add a nice healthy scoop of non-fat cottage cheese." Snack time is also an excellent chance to up your protein intake. "For ...
The U.S. Department of Agriculture’s Dietary Guidelines for Americans recommends 10% to 35% of your daily calories come from protein sources. A more common measure—which Amati and Sharp use ...
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
ShutterstockIt's no secret that protein is an essential nutrient for building muscle mass, supporting healthy weight management, and bolstering the immune system. But protein isn't vital only for ...