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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Opioids are a class of compounds that elicit analgesic (pain killing) effects in humans and animals by binding to the μ-opioid receptor within the central nervous system. The following table lists opioid and non-opioid analgesic drugs and their relative potencies .

  3. This experimental painkiller could be alternative to ... - AOL

    www.aol.com/experimental-painkiller-could...

    However, studies have shown that non-opioid treatments for acute pain can be just as if not more effective than opioids at treating some acute pain conditions, which could be where VX-548 comes in.

  4. Pain ladder - Wikipedia

    en.wikipedia.org/wiki/Pain_ladder

    If this is or becomes insufficient, a weak opioid is replaced by a strong opioid, such as morphine, diamorphine, fentanyl, buprenorphine, oxymorphone, oxycodone, or hydromorphone, while continuing the non-opioid therapy, escalating opioid dose until the patient is pain free or at the maximum possible relief without intolerable side effects.

  5. Analgesic - Wikipedia

    en.wikipedia.org/wiki/Analgesic

    An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...

  6. A New Pain Medication Could Reinforce the Disastrous ... - AOL

    www.aol.com/news/pain-medication-could-reinforce...

    Vertex Pharmaceuticals is trumpeting the results of clinical trials indicating that VX-548, its new, non-opioid analgesic, is effective at relieving post-surgical pain. While there is nothing ...

  7. Vertex non-opioid painkiller meets main goal in late ... - AOL

    www.aol.com/news/vertex-non-opioid-pain-drug...

    (Reuters) -Vertex Pharmaceuticals' experimental drug reduced acute, post-surgical pain without the risk of addiction, a major milestone in the company's decades-long efforts to bring a non-opioid ...

  8. Vertex Pharma scientist talks about the long road to ... - AOL

    www.aol.com/lifestyle/vertex-pharma-scientist...

    Vertex Pharmaceuticals recently reported positive results for a non-opioid painkiller, one of several medications the Boston-based drugmaker has been developing for various forms of pain. Patients ...

  9. Nefopam - Wikipedia

    en.wikipedia.org/wiki/Nefopam

    Nefopam, sold under the brand name Acupan among others, is a centrally acting, non-opioid painkilling medication, with central stimulant and sympathomimetic properties that is primarily used to treat moderate to severe pain.

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