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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [1] [2] In humans, the most significant compounds within this group are vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol). [2] [3]
In medical practice, a blood test for 25-hydroxy-vitamin D, 25(OH)D, is used to determine an individual's vitamin D status. [11] The name 25(OH)D refers to any combination of calcifediol (25-hydroxy-cholecalciferol), derived from vitamin D 3, and ercalcidiol (25-hydroxy-ergocalciferol), [1] derived from vitamin D 2. The first of these (also ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [3] to prevent and treat vitamin D deficiency [4] due to poor absorption by the intestines or liver disease. [5]
22-Dihydroergocalciferol is a form of vitamin D, also known as vitamin D 4. [2] It has the systematic name (5Z,7E)-(3S)-9,10-seco-5,7,10(19)-ergostatrien-3-ol. [1] Vitamin D 4 is found in certain mushrooms, being produced from ergosta-5,7-dienol (22,23-dihydroergosterol) instead of ergosterol. [3]
The 25-hydroxy vitamin D test segment dominated the market and accounted for the largest vitamin D testing market share in 2023. The 25-hydroxy vitamin D test is the most reliable method to measure the levels of vitamin D. The body's level of vitamin D can be determined accurately by the measurement of 25-hydroxyvitamin D content in the blood.
Ergosterol (ergosta-5,7,22-trien-3β-ol) is a sterol found in fungi, and named after ergot, the common name of members of the fungal genus Claviceps from which ergosterol was first isolated. Ergosterol is a component of yeast and other fungal cell membranes , serving many of the same functions that cholesterol serves in animal cells. [ 1 ]
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