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Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. [1] Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. [1] Other symptoms may include bone pain, chest pain, or itchiness. [1]
CHOP is the acronym for a chemotherapy regimen used in the treatment of non-Hodgkin lymphoma. CHOP consists of: CHOP consists of: C yclophosphamide , an alkylating agent which damages DNA by binding to it and causing the formation of cross-links
EPOCH is an intensive chemotherapy regimen intended for treatment of aggressive non-Hodgkin's lymphoma. [1] [2] It is often combined with rituximab. In this case it is called R-EPOCH or EPOCH-R.The R-EPOCH regimen consists of: Rituximab: an anti-CD20 monoclonal antibody, which has the ability to kill B cells, be they normal or malignant;
Non-Hodgkin lymphomas, which are defined as being all lymphomas except Hodgkin lymphoma, are more common than Hodgkin lymphoma. A wide variety of lymphomas are in this class, and the causes, the types of cells involved, and the prognoses vary by type. The number of cases per year of non-Hodgkin lymphoma increases with age.
Other treatments for non-Hodgkin’s lymphoma include radiation therapy, targeted drug therapy, and bone marrow transplant. Certain factors may increase the risk of developing this type of cancer ...
Overall, CNS involvement is observed in 2 to 27% of patients with aggressive systemic non-Hodgkin’s lymphoma. [5] 5% of patients with diffuse large B cell lymphoma, the most common type of non-Hodgkin lymphoma, result in SCNSL but account for most SCNSL cases. [3] Illustration depicting metastasis by haematogenous spread
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