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Anaphylaxis is a severe allergic reaction of rapid onset affecting many body systems. [5] [8] It is due to the release of inflammatory mediators and cytokines from mast cells and basophils, typically due to an immunologic reaction but sometimes non-immunologic mechanism. [8]
The immune system will produce immunoglobulin E, IgE, antibodies for each allergen. The antibodies will cause cells in the body to produce histamine. This histamine will act on different areas of the body (eyes, throat, nose, gastrointestinal tract, skin or lungs) to produce symptoms of an allergic reaction.
Food allergies rarely cause respiratory (asthmatic) reactions, or rhinitis. [24] Insect stings, food, antibiotics, and certain medicines may produce a systemic allergic response that is also called anaphylaxis; multiple organ systems can be affected, including the digestive system, the respiratory system, and the circulatory system.
Mast cell activation syndrome (MCAS) is a term referring to one of two types of mast cell activation disorder (MCAD); the other type is idiopathic MCAD. [1] MCAS is an immunological condition in which mast cells, a type of white blood cell, inappropriately and excessively release chemical mediators, such as histamine, resulting in a range of chronic symptoms, sometimes including anaphylaxis or ...
Mast cells serve the same general functions in the body and central nervous system, such as effecting or regulating allergic responses, innate and adaptive immunity, autoimmunity, and inflammation. [4] [17] Across systems, mast cells serve as the main effector cell through which pathogens can affect the gut–brain axis. [18] [19]
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An extremely serious form of an allergic reaction is called anaphylaxis. One form of treatment is the administration of sterile epinephrine to the person experiencing anaphylaxis, which suppresses the body's overreaction to the allergen, and allows for the patient to be transported to a medical facility.
Whether it’s your spouse, partner, best friend or a co-worker, using the buddy system will help remind you to stay true to your desire to drink less. It's also more fun to sip a Shirley Temple ...