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  2. Arterial blood gas test - Wikipedia

    en.wikipedia.org/wiki/Arterial_blood_gas_test

    In the context of arterial blood gases, the most common occurrence will be that of respiratory acidosis. Carbon dioxide is dissolved in the blood as carbonic acid, a weak acid; however, in large concentrations, it can affect the pH drastically. Whenever there is poor pulmonary ventilation, the carbon dioxide levels in the blood are expected to ...

  3. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    Carbon dioxide, a by-product of cellular respiration, is dissolved in the blood, where it is taken up by red blood cells and converted to carbonic acid by carbonic anhydrase. Most of the carbonic acid then dissociates to bicarbonate and hydrogen ions. The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of ...

  4. Carbonic acid - Wikipedia

    en.wikipedia.org/wiki/Carbonic_acid

    Carbonic acid is a chemical compound with the chemical formula H 2 C O 3. The molecule rapidly converts to water and carbon dioxide in the presence of water. However, in the absence of water, it is quite stable at room temperature .

  5. Carbaminohemoglobin - Wikipedia

    en.wikipedia.org/wiki/Carbaminohemoglobin

    Carbonic anhydrase catalyzes the conversion of carbon dioxide and water into carbonic acid. This molecule breaks down into bicarbonate and hydrogen ions. This break down process occurs in red blood cells. Ultimately, the concentration of bicarbonate ions in the bloodstream affects the formation of the protein carbaminohemoglobin in the body. [11]

  6. Bicarbonate - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate

    It is isoelectronic with nitric acid HNO 3. The bicarbonate ion carries a negative one formal charge and is an amphiprotic species which has both acidic and basic properties. It is both the conjugate base of carbonic acid H 2 CO 3; and the conjugate acid of CO 2− 3, the carbonate ion, as shown by these equilibrium reactions: CO 2− 3 + 2 H 2 ...

  7. Carbonic anhydrase - Wikipedia

    en.wikipedia.org/wiki/Carbonic_anhydrase

    Carbonic anhydrase is critical to hemoglobin function via the Bohr effect which catalyzes the hydration of carbon dioxide to form carbonic acid and rapidly dissociate into water. [4] Essentially an increase in carbon dioxide results in lowered blood pH, which lowers oxygen-hemoglobin binding. [5]

  8. Hypercapnia - Wikipedia

    en.wikipedia.org/wiki/Hypercapnia

    Since carbon dioxide is in equilibrium with carbonic acid in the blood, hypercapnia drives serum pH down, resulting in respiratory acidosis. Clinically, the effect of hypercapnia on pH is estimated using the ratio of the arterial pressure of carbon dioxide to the concentration of bicarbonate ion, P a C O 2 / H C O 3 − {\displaystyle {P_{a_{CO ...

  9. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    Acid-base disturbances such as lactic acidosis are typically first assessed using arterial blood gas tests. Testing of venous blood is also available as an alternative as they are effectively interchangeable. [3] Normally resulting lactate concentrations are in the range indicated below: [16]

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