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[8] [50] Subclinical hypothyroidism is estimated to affect approximately 2% of children; in adults, subclinical hypothyroidism is more common in the elderly, and in White people. [49] There is a much higher rate of thyroid disorders, the most common of which is hypothyroidism, in individuals with Down syndrome [30] [62] and Turner syndrome. [30]
Myxedema coma is an extreme or decompensated form of hypothyroidism and while uncommon, is potentially lethal. [1] [2] [3] A person may have laboratory values identical to a "normal" hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly.
Hypothermia is defined as a body core temperature below 35.0 °C (95.0 °F) in humans. [2] Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion.
Thyroid disease is a medical condition that affects the function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.
The thyroid hormones have a wide range of effects on the human body. These include: Metabolic. The thyroid hormones increase the basal metabolic rate and have effects on almost all body tissues. [26] Appetite, the absorption of substances, and gut motility are all influenced by thyroid hormones. [27]
Myxedema coma is rare but often fatal. It occurs most often in elderly women and may be mistaken for one of the chronic debilitating diseases common to this age group. [9] Though the exact cause of myxedema is still unclear, a wealth of research has demonstrated the importance of iodine. [10]
Patients on LT 4 monotherapy may have blood T 3 levels low or below the normal range, [76] [72] and/or may have local T 3 deficiency in some tissues. [ 84 ] Although both molecules can have biological effects, thyroxine (T 4 ) is considered the "storage form" of thyroid hormone, while tri-iodothyronine (T 3 ) is considered the active form used ...
Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
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