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Midazolam can be given by mouth, intravenously, by injection into a muscle, by spraying into the nose, or through the cheek. [12] [14] When given intravenously, it typically begins working within five minutes; when injected into a muscle, it can take fifteen minutes to begin working; [12] when taken orally, it can take 10–20 minutes to begin ...
Can be given rectally by trained care-givers. Midazolam (N/A). Increasingly being used as an alternative to diazepam. This water-soluble drug is squirted into the side of the mouth but not swallowed. It is rapidly absorbed by the buccal mucosa. Lorazepam (1972). Given by injection in hospital.
Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle. In medicine , it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles have larger and more numerous blood vessels than subcutaneous tissue, leading to faster absorption than ...
Midazolam collects in the body's fatty tissues, so a possible complication includes prolonged sedation. As a result, the elderly, the obese, and those with kidney or liver disease are more vulnerable to prolonged sedation with midazolam. Respiratory depression is also associated with midazolam when given in high doses.
"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual ...
You can also use padding, such as cotton pads or gauze, on blisters in high-pressure areas, like on your feet, the AAD says. Place the padding over the blister and cover with a bandage. Be sure to ...
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Benzodiazepines are also used to calm the acutely agitated individual and can, if required, be given via an intramuscular injection. [68] They can sometimes be effective in the short-term treatment of psychiatric emergencies such as acute psychosis as in schizophrenia or mania , bringing about rapid tranquillization and sedation until the ...
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