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Statins are the most common medication for high cholesterol. They work by blocking an enzyme that your liver needs to make cholesterol. [14] Statins also improve your liver’s ability to remove ...
Five main classes of agents can be used to treat hyperlipidemia, a condition that comes with high cholesterol levels. Those are bile acid sequestrants, nicotinic acid, fibric acid derivatives, probucol and HMG-CoA-reductase inhibitors. Cerivastatin mainly acts by competitively inhibiting HMG-CoA-reductase, which is the rate-limiting enzyme step ...
Statins may improve quality of life when used in people without existing cardiovascular disease (i.e. for primary prevention). [74] Statins decrease cholesterol in children with hypercholesterolemia, but no studies as of 2010 show improved outcomes [76] and diet is the mainstay of therapy in childhood. [39]
The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12] The manufacturer Pfizer reported sales of US$12.4 billion in 2008. [13] Patient compliance with statin usage is problematic despite robust evidence of the benefits. [14] [15]
In fact, about 7% of U.S. children and adolescents ages 6 to 19 have high total cholesterol. Ideally, you shouldn’t wait until you’re diagnosed with high cholesterol to start being mindful of ...
There can be a genetic link for high cholesterol, but for the majority of us, lifestyle and diet will be the key deciding factors in how high it goes.
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