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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. U.S. FDA Approves ELIQUIS® (apixaban) to Reduce the ... - AOL

    www.aol.com/news/2013-01-02-us-fda-approves...

    U.S. FDA Approves ELIQUIS ® (apixaban) to Reduce the Risk of Stroke and Systemic Embolism in Patients with Nonvalvular Atrial Fibrillation ELIQUIS Demonstrated Superior Risk Reductions Versus ...

  5. CHA2DS2–VASc score - Wikipedia

    en.wikipedia.org/wiki/CHA2DS2–VASc_score

    If the patient is 'low risk' using the CHA 2 DS 2-VASc score (that is, 0 in males or 1 in females), no anticoagulant therapy is recommended. In males with 1 stroke risk factor (that is, a CHA 2 DS 2 -VASc score=1), antithrombotic therapy with OAC may be considered, and people's values and preferences should be considered. [ 24 ]

  6. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]

  7. Bitcoin could soar to $500,000 if the US starts buying the ...

    www.aol.com/bitcoin-could-soar-500-000-195728585...

    Bitcoin could soar to $500,000 if Trump creates a national reserve, Bitwise CIO Matt Hougan said.. The US creating a national stockpile will influence other countries to follow suit, he predicted ...

  8. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  9. Obesity Rates in the U.S. Drop for the First Time in a Decade ...

    www.aol.com/obesity-rates-u-drop-first-204508332...

    For the first time in a decade, rates of adult obesity in the United States have dropped, a new study has found.. The study followed nearly 17 million people, the majority of whom were in the 26 ...