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An example of a well-studied [44] genetic biomarker in schizophrenia is the single nucleotide polymorphism in the HLA-DQB1 gene, which is part of the human leukocyte antigen (HLA) complex. A G to C replacement on position 6672 predicts risk of agranulocytosis , a side effect of clozapine that can be fatal.
Additionally, there has been an improved motion correction and harmonization, which both aid in the generalizability and replication of findings in schizophrenia research. [3] Recent studies have used fMRI to explore specific brain networks, such as the salience network and default mode network , to understand their roles in schizophrenia ...
The Schizophrenia Cognition Rating Scale (SCoRS) is a 20 item interview-based clinical assessment that evaluates cognitive deficits and the degree to which these deficits impair patients’ day-to-day functioning. [1] It was originally developed in 2001 at the Duke University Medical Center by Dr. Richard Keefe and is licensed through WCG Clinical.
At risk mental state is the clinical presentation of those considered at risk of developing psychosis or schizophrenia. [1] Such states were formerly considered treated as prodromes, emerging symptoms of psychosis, but this view is no longer prevalent as a prodromal period can not be confirmed unless the emergence of the condition has occurred.
The mental status examination (MSE) is an important part of the clinical assessment process in neurological and psychiatric practice. It is a structured way of observing and describing a patient's psychological functioning at a given point in time, under the domains of appearance, attitude, behavior, mood and affect, speech, thought process, thought content, perception, cognition, insight, and ...
The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness .
The following diagnostic systems and rating scales are used in psychiatry and clinical psychology. This list is by no means exhaustive or complete. This list is by no means exhaustive or complete. For instance, in the category of depression, there are over two dozen depression rating scales that have been developed in the past eighty years.
Interpretation of schizophrenia is a 756-page book divided in 45 chapters. Arieti begins his book stating that it is difficult to define schizophrenia. He asks if schizophrenia is an illness and answers in the negative, since the disorder is not understood in classic Virchowian criterion of cellular pathology.
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