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A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]
A549 cells share the same characteristics with the alveolar type II cells. This are type II pneumocytes crucial for lung homeostasis, and regeneration upon damage. For research purposes to unravel different molecular mechanisms leading to lung diseases, A549 cells serves as a good model to which translational research can be relied upon.
This page was last edited on 23 November 2019, at 17:55 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...
1. All of these words sound like a specific letter in the alphabet. 2. These items are known for their notched edges. 3. Expressions that show mild frustration. 4. Features of a flowing body of water.
A549 may refer to: A549 (cell line), a carcinomic human alveolar basal epithelial cell; A549 road (Wales), a road in Great Britain This page was last edited on 27 ...
The cells were isolated from the pleural effusion of a 25-year-old Caucasian male with a lung adenocarcinoma. [citation needed] The ERBB2 gene is overexpressed in Calu-3 cells, and plays a role in aggressive cancer proliferation. The Calu-3 cell line grows as an adherent monolayer and overexpresses the ERBB2 gene, leading to
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