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Prophase II of meiosis is very similar to prophase of mitosis. The most noticeable difference is that prophase II occurs with a haploid number of chromosomes as opposed to the diploid number in mitotic prophase. [12] [10] In both animal and plant cells chromosomes may de-condense during telophase I requiring them to re-condense in prophase II.
Although this machinery is conserved through evolution, [48] [49] in vertebrates most cohesin molecules are released in prophase, independently of the presence of the APC/C, in a process dependent on Polo-like 1 and Aurora B. [50] Yet it has been shown that a small quantity of Scc1 remains associated to centromeres in human cells until ...
[18]: 27 In this stage of prophase I, individual chromosomes—each consisting of two replicated sister chromatids—become "individualized" to form visible strands within the nucleus. [ 18 ] : 27 [ 19 ] : 353 The chromosomes each form a linear array of loops mediated by cohesin , and the lateral elements of the synaptonemal complex assemble ...
Synapsis or Syzygy is the pairing of two chromosomes that occurs during meiosis. It allows matching-up of homologous pairs prior to their segregation, and possible chromosomal crossover between them. Synapsis takes place during prophase I of meiosis. When homologous chromosomes synapse, their ends are first attached to the nuclear envelope.
The two chromosomes which pair are referred to as non-sister chromosomes, since they did not arise simply from the replication of a parental chromosome. Recombination between non-sister chromosomes at meiosis is known to be a recombinational repair process that can repair double-strand breaks and other types of double-strand damage. [ 2 ]
Zygotene (from greek "paired threads" [1]) is the second stage of prophase I during meiosis, the specialized cell division that reduces the chromosome number by half to produce haploid gametes. It follows the Leptotene stage and is followed by Pachytene stage.
In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...
In prophase I of meiosis I, each chromosome is aligned with its homologous partner and pairs completely. In prophase I, the DNA has already undergone replication so each chromosome consists of two identical chromatids connected by a common centromere. [10] During the zygotene stage of prophase I, the homologous chromosomes pair up with each ...