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  2. Legionella pneumophila - Wikipedia

    en.wikipedia.org/wiki/Legionella_pneumophila

    Legionella pneumophila, the primary causative agent for Legionnaire's disease, is an aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium. [1] [2] L. pneumophila is a intracellular parasite that preferentially infects soil amoebae and freshwater protozoa for replication.

  3. Legionnaires' disease - Wikipedia

    en.wikipedia.org/wiki/Legionnaires'_disease

    The fatality rate of Legionnaires' disease has ranged from 5–30% during various outbreaks and approaches 50% for nosocomial infections, especially when treatment with antibiotics is delayed. [38] Hospital-acquired Legionella pneumonia has a fatality rate of 28%, and the principal source of infection in such cases is the drinking-water ...

  4. Levofloxacin - Wikipedia

    en.wikipedia.org/wiki/Levofloxacin

    As of 2016, the US Food and Drug Administration (FDA) recommended that "serious side effects associated with fluoroquinolone antibacterial drugs generally outweigh the benefits for patients with acute sinusitis, acute bronchitis, and uncomplicated urinary tract infections who have other treatment options. For patients with these conditions ...

  5. Sparfloxacin - Wikipedia

    en.wikipedia.org/wiki/Sparfloxacin

    Quinolones can enter cells easily and therefore are often used to treat intracellular pathogens such as Legionella pneumophila and Mycoplasma pneumoniae. For many gram-negative bacteria DNA gyrase is the target, whereas topoisomerase IV is the target for many gram-positive bacteria. Eukaryotic cells do not contain DNA gyrase or topoisomerase IV.

  6. What is Legionnaires' disease? - AOL

    www.aol.com/news/2015-08-04-what-is-legionnaires...

    You can contract Legionnaire's disease by inhaling the bacteria (legionella), but NOT from person to person contact. Because it is a disease that affects the lungs, older adults, smokers and ...

  7. Lower respiratory tract infection - Wikipedia

    en.wikipedia.org/wiki/Lower_respiratory_tract...

    Procalcitonin-guided antibiotic therapy also reduced the antibiotic use duration by 2.4 days, and there were fewer antibiotic side effects. This means that procalcitonin is useful for guiding whether to use antibiotics for acute respiratory infections and the duration of the antibiotic. [23]

  8. Antibiotic side effects left me barely able to walk - AOL

    www.aol.com/news/antibiotic-side-effects-left...

    The UK medicines regulator MHRA warned that fluoroquinolones were linked to rare but occasionally severe and irreversible side effects, including tendon rupture, muscle and joint pain and nerve ...

  9. Dangerous side effect of popular antibiotic - AOL

    www.aol.com/lifestyle/dangerous-side-effect...

    According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.

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