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Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations .
The cerebrospinal fluid (CSF) within the skull and spine provides further protection and also buoyancy, and is found in the subarachnoid space between the pia mater and the arachnoid mater. [citation needed] The CSF that is produced in the ventricular system is also necessary for chemical stability, and the provision of nutrients needed by the ...
The ependyma is made up of ependymal cells called ependymocytes, a type of glial cell.These cells line the ventricles in the brain and the central canal of the spinal cord, which become filled with cerebrospinal fluid.
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [ 14 ]
The granulations are thought to mediate the draining of cerebrospinal fluid (CSF) from the subarachnoid space into the venous system. [1] The largest and most numerous granulations lie along the superior sagittal sinus; they are however present along other dural sinuses as well.
The subcommissural organ/Reissner's fiber complex is thought to be involved in the reabsorption and circulation of the cerebrospinal fluid, and with functions related to electrolyte and water balance. [4] [5] One of the proteins secreted by the subcommissural organ, and which is present in Reissner's fiber, is spondin.
According to this model, cerebrospinal fluid (CSF), an ultrafiltrated plasma fluid secreted by choroid plexuses in the cerebral ventricles, flows into the paravascular space around cerebral arteries, contacts and mixes with interstitial fluid (ISF) and solutes within the brain parenchyma, and exits via the cerebral venous paravascular spaces ...
Aqueductal stenosis is a narrowing of the aqueduct of Sylvius which blocks the flow of cerebrospinal fluid (CSF) in the ventricular system. Blockage of the aqueduct can lead to hydrocephalus, specifically as a common cause of congenital and/or obstructive hydrocephalus. [1] [2]