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The histological picture involves thinner, weaker attachments of the skin lesion itself to the normal skin – resulting in easier dislodgement. The formation of new blisters upon slight pressure (direct Nikolsky) and shearing of the skin due to rubbing (indirect Nikolsky) is a sign of pemphigus vulgaris, albeit not a 100% reliable diagnosis. [8]
Finally, the most important differential diagnosis is scleromyxedema. Localized lichen myxedematosus and scleromyxedema were once thought to be the same disease, but they are actually part of a spectrum in the context of primary cutaneous mucinoses. Clinical, histologic, and laboratory findings can help differentiate between the two disorders. [2]
DermNet also provides an interactive tool, DermDiag, which allows users to assess their own skin conditions. The tool allows the user to input increasingly specific levels of information regarding their condition, starting from location of ailment, up to number of blemishes, and provides the user with potential diagnoses.
A skin biopsy is used to diagnose syringocystadenoma papilliferum. Characteristics of Syringocystadenoma papilliferum are dilated capillaries and a dense infiltration of plasma cells. [1] Differential diagnoses include papillary eccrine adenoma, warty dyskeratoma, tubular apocrine adenoma, and hidradenoma papilliferum. [3]
Stress, dry skin, winter, poor immune function, Parkinson disease [4] Diagnostic method: Based on symptoms [4] Differential diagnosis: Psoriasis, atopic dermatitis, tinea capitis, rosacea, systemic lupus erythematosus [4] Treatment: Humidifier: Medication: Antifungal cream, anti-inflammatory agents, coal tar, phototherapy [3] Frequency
Diagnosis of nummular dermatitis is largely via clinical observation. Biopsies are typically not necessary, and cannot be used to rule out other atopic dermatitis or other eczemas. [ 9 ] [ 10 ] However, patch testing may be employed to rule out irritants ( contact dermatitis ) as a cause.
The diagnosis is frequently made by treating the initial triggering skin problem and observing the improvement in the eczematous rash. Both the initial skin problem and the id reaction must be observed to make the diagnosis. [5] [6] Not all dyshidrotic rashes are id reactions, but id reactions are often dyshidrotic-like. [2]
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
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