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There can be damage either to the ear, whether the external or middle ear, to the cochlea, or to the brain centres that process the aural information conveyed by the ears. Damage to the middle ear may include fracture and discontinuity of the ossicular chain. Damage to the inner ear (cochlea) may be caused by temporal bone fracture. People who ...
The ear canal is cleaned via earwax, which naturally migrates to the auricle. The ear develops from the first pharyngeal pouch and six small swellings that develop in the early embryo called otic placodes, which are derived from the ectoderm. The ear may be affected by disease, including infection and traumatic damage.
There can be damage either to the ear, whether the external or middle ear, to the cochlea, or to the brain centers that process the aural information conveyed by the ears. Damage to the middle ear may include fracture and discontinuity of the ossicular chain. [79] [80] Damage to the inner ear (cochlea) may be caused by temporal bone fracture ...
Sensory hearing loss often occurs as a consequence of damaged or deficient cochlear hair cells. [disputed – discuss] Hair cells may be abnormal at birth or damaged during the lifetime of an individual. There are both external causes of damage, including infection, and ototoxic drugs, as well as intrinsic causes, including genetic mutations.
One study involves the replacement of damaged hair cells with regenerated cells, via the mechanism of gene transfer of atonal gene Math1 to pluripotent stem cells within the inner ear. [133] Other atonal genes are being studied to induce regeneration of hair cells in the inner ear.
AIED is generally caused by either antibodies or immune cells that cause damage to the inner ear. There are several theories that propose a cause of AIED: Bystander damage – Physical damage to the inner ear may lead to cytokine release that signals for an immune response. This may be a component of the "attack/remission cycle" of AIED. [9]
There are various treatment methods available depending on how severe the acoustic trauma is. Acoustic trauma cannot be reversed as of today. The goal of treatment is to protect the ear from further damage. [9] Below are possible preventive measures and treatment methods that could help in cases of acoustic trauma
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent.