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Lactobacillus is a genus of gram-positive, aerotolerant anaerobes or microaerophilic, rod-shaped, non-spore-forming bacteria. [2] [3] Until 2020, the genus Lactobacillus comprised over 260 phylogenetically, ecologically, and metabolically diverse species; a taxonomic revision of the genus assigned lactobacilli to 25 genera (see § Taxonomy below).
Studies involving L. acidophilus and Bifidobacterium suggest that these microbes inhibit the growth of facultative anaerobic bacteria, which tends to increase during antibiotic treatment. As a result, it is seen that probiotics can alter and prevent changes in the intestinal microflora caused by antibiotics. [11]
LACTIN-V, also known as CTV-05 or as Lactobacillus crispatus CTV-05, is a live biopharmaceutical medication containing a strain of Lactobacillus crispatus (L. crispatus) which is under development for the treatment of urinary tract infections (UTIs) and bacterial vaginosis (BV).
LACTIN-V is a live biopharmaceutical medication containing the vaginally important Lactobacillus crispatus which is under development for the treatment of bacterial vaginosis and recurrent urinary tract infections. [68] [69] [70] It has shown initial effectiveness in considerably reducing recurrence of bacterial vaginosis following antibiotic ...
Lactocillin is a thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria Lactobacillus gasseri. Lactocillin was discovered and purified in 2014. [1] Lactobacillus gasseri is one of the four Lactobacillus bacteria found to be most common in the human vaginal microbiome. [2]
Lactobacillus crispatus is a normal inhabitant of the lower reproductive tract in healthy women. [17] [18] Functionally, like other lactic acid-producing bacteria, it may prevent infections through production of lactic acid, thereby lowering the pH. [19] Condom use was correlated with increased colonization of Lactobacillus crispatus in the ...
The amount and type of bacteria present have significant implications for an individual's overall health. [2] The primary colonizing bacteria of a healthy individual are of the genus Lactobacillus, [3] such as L. crispatus, and the lactic acid they produce is thought to protect against infection by pathogenic species. [4]
In Lactobacillus acidophilus, which can be found in the gastrointestinal tract, quorum sensing is important for bacterial interaction when considering biofilm formation and toxin secretion. [14] In L. acidophilus , along with many other bacteria, the luxS -mediated quorum sensing is involved in the regulation of behavior.