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  2. Trazodone - Wikipedia

    en.wikipedia.org/wiki/Trazodone

    Trazodone, sold under many brand names, [1] is an antidepressant medication, [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20]

  3. Median lethal dose - Wikipedia

    en.wikipedia.org/wiki/Median_lethal_dose

    In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  4. List of adverse effects of trazodone - Wikipedia

    en.wikipedia.org/wiki/List_of_adverse_effects_of...

    This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.

  5. Median toxic dose - Wikipedia

    en.wikipedia.org/wiki/Median_toxic_dose

    The median toxic dose encompasses the category of toxicity that is greater than half maximum effective concentration (ED 50) but less than the median lethal dose (LD 50). However, for some highly potent toxins (ex. lofentanil , botulinum toxin ) the difference between the ED 50 and TD 50 is so minute that the values assigned to them may be ...

  6. Lethal dose - Wikipedia

    en.wikipedia.org/wiki/Lethal_dose

    In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per kilogram of subject body weight) at which a given percentage of subjects will die.

  7. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. . The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred spee

  8. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    It is desirous for the value of LD 50 to be as large as possible, to decrease risk of lethal effects and increase the therapeutic window. In the above formula, TI safety increases as the difference between LD 50 and ED 50 increases—hence, a higher safety-based therapeutic index indicates a larger therapeutic window, and vice versa.

  9. List of antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_antidepressants

    This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.

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