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Goblet cells are typically found in the respiratory, reproductive and lower gastrointestinal tract and are surrounded by other columnar cells. [1] Biased differentiation of airway basal cells in the respiratory epithelium , into goblet cells plays a key role in the excessive mucus production, known as mucus hypersecretion seen in many ...
During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus. These stem cells can differentiate into either an absorptive (enterocytes) or secretory (Goblet cells, Paneth cells, enteroendocrine cells) lineages. [3]
These are known as non-ciliated columnar epithelium. Non-ciliated simple columnar epithelium is made up of glandular goblet cells which secrete mucin to form mucus. [1] The rest of the cell is made up of cytoplasm with membrane bound secretory granules which secrete the mucin, and are found towards the apical surface of the cell. [1]
Goblet cell; Pulmonary neuroendocrine cell [2] Digestive system. Stomach. Gastric enteroendocrine cells. G cell; Delta cell; Enterochromaffin-like cell;
The epithelium, the most exposed part of the mucosa, is a glandular epithelium with many goblet cells. Goblet cells secrete mucus , which lubricates the passage of food along and protects the intestinal wall from digestive enzymes.
Goblet cells secrete the mucus layer which protects the epithelium from the luminal contents. Enteroendocrine cells secrete various gastrointestinal hormones including secretin, pancreozymin, enteroglucagon among others. Subsets of sensory intestinal epithelial cells synapse with nerves, [9] and are known as neuropod cells. [10]
The submucosal glands are a companion to goblet cells which also produce mucus, and are found lining the same tubes. [2] In the upper respiratory system of mammals there are submucosal glands in the airways, notably in the sinuses, the trachea and the bronchial tubes. [1] In the visual systems of mammals. In the auditory systems of mammals.
Mucous glands, also known as muciparous glands, are found in several different parts of the body, and they typically stain lighter than serous glands during standard histological preparation. Most are multicellular, but goblet cells are single-celled glands.