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Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [ 1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into lymphatic or ...
Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
Less than 1 per 100,000 per year. Chronic myelomonocytic leukemia ( CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. In CMML, there are increased numbers of monocytes and immature blood cells ( blasts ...
Frequency. 904,000 (2015) [ 6] Deaths. 60,700 (2015) [ 7] Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss ...
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia characterized by an aggressive malignant neoplasm of the bone marrow. [6] Acute lymphoblastic leukemia (ALL) is a condition where immature white blood cells accumulate in the bone marrow, subsequently crowding out normal white blood cells [7] and creating a build-up in the liver, spleen, and lymph nodes.
Lymphoma in animals. Lymphoma in a Golden Retriever. Lymphoma (lymphosarcoma) in animals is a type of cancer defined by a proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver and spleen. The disease also may occur in the eye, skin, and gastrointestinal tract .
Langerhans cell histiocytosis ( LCH) is an abnormal clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes . Symptoms range from isolated bone lesions to multisystem disease. [ 1] LCH is part of a group of syndromes called histiocytoses, which are characterized by an ...
Mastocytomas in dogs occur mainly in the skin and subcutaneous tissue. Very rarely, they are found in internal organs such as the small intestine, [5] the mucosa of the mouth, [6] the nasal mucosa [7] or the conjunctiva. [8] About 20% of all skin tumors [9] and 6% of all tumors [10] in dogs are mastocytomas.