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Patch clamp of a nerve cell within a slice of brain tissue. The pipette in the photograph has been marked with a slight blue color. Many patch clamp amplifiers do not use true voltage clamp circuitry, but instead are differential amplifiers that use the bath electrode to set the zero current (ground) level.
Voltage and current errors: SEV-c circuitry does not actually measure the voltage of the cell being clamped (as does a two-electrode clamp). The patch-clamp amplifier is like a two-electrode clamp, except the voltage measuring and current passing circuits are connected (in the two-electrode clamp, they are connected through the cell). The ...
Patch-clamp automation instrumentation became commercially available in 2003. Due to the initial high cost this near to 20 years old technology was originally intended to serve the biotech and pharmaceutical industries but it has since also been used in academia and nonprofit settings, in connection and coexisting with other associated or ...
During the 1970s, the MC-2300 was an expensive piece of audio equipment, with a retail price of $1799 by the time of its discontinuation in 1980. [1] That being said, its outstanding power and sound production quality made it a valued part of many recording studios and although some people prefer the sound of tube amplifiers, the overall greater reliability and freedom from repair of the newer ...
A negative clamp is the opposite of this—this clamp outputs a purely negative waveform from an input signal. A bias voltage between the diode and ground offsets the output voltage by that amount. For example, an input signal of peak value 5 V (V INpeak = 5 V) is applied to a positive clamp with a bias of 3 V (V BIAS = 3 V), the peak output ...
It is well known for having produced the Marantz Classic series of amplifiers for Marantz Japan from 1996 to 1998 (Marantz Model 7 / 7C, Model 8B, Model 9), as well as the VAC-designed Model 66 integrated amplifier. In addition, it redeveloped and produced the first 200 recreations of the LA-2A leveling amplifier for Universal Audio in 1998.
The current-feedback operational amplifier (CFOA or CFA) is a type of electronic amplifier whose inverting input is sensitive to current, rather than to voltage as in a conventional voltage-feedback operational amplifier (VFA). The CFA was invented by David Nelson at Comlinear Corporation, and first sold in 1982 as a hybrid amplifier, the CLC103.
A class-B push–pull amplifier is more efficient than a class-A power amplifier because each output device amplifies only half the output waveform and is cut off during the opposite half. It can be shown that the theoretical full power efficiency (AC power in load compared to DC power consumed) of a push–pull stage is approximately 78.5%.
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