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The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. [9] Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less ...
There are two different forms of the estrogen receptor, usually referred to as α and β, each encoded by a separate gene (ESR1 and ESR2, respectively).Hormone-activated estrogen receptors form dimers, and, since the two forms are coexpressed in many cell types, the receptors may form ERα (αα) or ERβ (ββ) homodimers or ERαβ (αβ) heterodimers. [3]
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: Dual ET Receptor Antagonists, which affect both endothelin A (ET A) and B receptors (ET B) [1] aprocitentan, bosentan, macitentan, tezosentan; Selective ET A Receptor Antagonists, which affect endothelin A receptors
Activision Publishing, Inc. is an American video game publisher based in Santa Monica, California.It serves as the publishing business for its parent company, Activision Blizzard, and consists of several subsidiary studios.
The advanced Kontakt-5 explosive reactive armour on this T-90S is arranged in pairs of plates, giving the turret its prominent triangular profile.. An element of explosive reactive armour (ERA) is made of either a sheet or slab of high explosive sandwiched between two metal plates, or multiple "banana shaped" rods filled with high explosive which are referred to as shaped charges.
Engineering Research Associates, commonly known as ERA, was a pioneering computer firm from the 1950s. ERA became famous for their numerical computers, but as the market expanded they became better known for their drum memory systems. They were eventually purchased by Remington Rand and merged into their UNIVAC department.
In May 2022, QA testers of Activision Blizzard subsidiary Raven Software went public as the Game Workers Alliance (GWA) with the support of Campaign to Organize Digital Employees-CWA and voted to unionize with a count of 19 – 2 in favor. [74] The National Labor Relations Board recognized GWA as a union. [75] [76]
The Eigensystem realization algorithm (ERA) is a system identification technique popular in civil engineering, in particular in structural health monitoring [citation needed]. ERA can be used as a modal analysis technique and generates a system realization using the time domain response (multi-)input and (multi-)output data. [ 1 ]