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Kava or kava kava (Piper methysticum: Latin 'pepper' and Latinized Greek 'intoxicating') is a plant in the pepper family, native to the Pacific Islands. [1] The name kava is from Tongan and Marquesan, meaning 'bitter.’ [1] Other names for kava include ʻawa (), [2] ʻava (), yaqona or yagona (), [3] sakau (), [4] seka (), [5] and malok or malogu (parts of Vanuatu). [6]
This, along with several other catecholamines, may be responsible for the purported attention-promoting effects of kava. Unlike the other major kavalactones, desmethoxyyangonin does not appear to act as a GABA A receptor positive allosteric modulator. [3] Desmethoxyyangonin has marked activity on the induction of CYP3A23. [4]
Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels. [1] How this effect is mediated, and to what extent this mechanism is involved in the anxiolytic and analgesic effects of kavalactones on the central nervous system, is unknown.
A growing body of research and numerous anecdotal reports link cannabis with several health benefits.
On the positive side, a 2020 research article published in BMC Psychiatry concluded that there is "encouraging, albeit embryonic" (meaning, early stage) evidence for using medicinal cannabis to ...
A participant in a study on the effects of cannabis, shows the marijuana flowers he has grown in his backyard, in Longmont, Colorado, U.S., December 19, 2019. REUTERS/Kevin Mohatt
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.