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Rheumatology (from Greek ῥεῦμα (rheûma) 'flowing current') is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. [1]
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments.Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones).
To improve the diagnostic capture rate in the early detection of patients with RA and to risk stratify these individuals, the rheumatology field continues to seek complementary markers to both RF and anti-CCP. 14-3-3η is one such marker that complements RF and anti-CCP, along with other serological measures like C-reactive protein. In a ...
Rheumatology Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS 3 PE ) is a rare syndrome identified by symmetric polyarthritis , synovitis , acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor . [ 2 ]
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Rheumatology Spondyloarthritis ( SpA ), also known as spondyloarthropathy , is a collection of clinical syndromes that are connected by genetic predisposition and clinical manifestations. [ 1 ] The best-known clinical subtypes are enteropathic arthritis (EA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and reactive arthritis (ReA ...
Osteoarthritis in the left hand index finger of an affected patient Dupuytren's contracture is characterised by the thickening and tightening of fibrous tissue layers in the palm. [ 3 ] However, the causes of this progressive condition remain unknown.
The American College of Rheumatology (ACR; [1] until 1985 called American Rheumatism Association [2]) is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocacy and practice support relating to the care of people with arthritis and rheumatic and musculoskeletal diseases.