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  2. The Code Breaker - Wikipedia

    en.wikipedia.org/wiki/The_Code_Breaker

    The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race is a non-fiction book authored by American historian and journalist Walter Isaacson. Published in March 2021 by Simon & Schuster, it is a biography of Jennifer Doudna, the winner of the 2020 Nobel Prize in Chemistry for her work on the CRISPR system of gene ...

  3. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    In June 2021, the first, small clinical trial of intravenous CRISPR gene editing in humans concluded with promising results. [42] [43] In September 2021, the first CRISPR-edited food went on public sale in Japan. Tomatoes were genetically modified for around five times the normal amount of possibly calming [44] GABA. [45]

  4. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  5. CRISPR/Cas tools - Wikipedia

    en.wikipedia.org/wiki/CRISPR/Cas_Tools

    CRISPR-Cas design tools are computer software platforms and bioinformatics tools used to facilitate the design of guide RNAs (gRNAs) for use with the CRISPR/Cas gene editing system. CRISPR-Cas [ edit ]

  6. Jennifer Doudna - Wikipedia

    en.wikipedia.org/wiki/Jennifer_Doudna

    The CRISPR system created a new straightforward way to edit DNA and there was a rush to patent the technique. [6] Doudna and UC Berkeley collaborators applied for a patent and so did a group at the Broad Institute affiliated with the Massachusetts Institute of Technology and Harvard. [47] Feng Zhang at the Broad Institute had shown that CRISPR ...

  7. Off-target genome editing - Wikipedia

    en.wikipedia.org/wiki/Off-target_genome_editing

    In order for gene editing technologies to make the leap towards safe and widespread use in the clinic, the rate of off-target modification needs to be rendered obsolete. The safety of gene therapy treatment is of utmost concern, especially during clinical trials when off-target modifications can block the further development of a candidate ...

  8. Gene editing - Wikipedia

    en.wikipedia.org/wiki/Gene_editing

    Genome editing, a type of genetic engineering; Gene therapy, the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease; CRISPR gene editing, a genetic engineering technique.CRISPR are termed as (site directed nucleases) SDN since they target specific part of genome, there are 3 different categories of ...

  9. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    The impact of human gene editing on resistance to HIV infection and other body functions in experimental infants remains controversial. The World Health Organization has issued three reports on the guidelines of human genome editing since 2019, [41] and the Chinese government has prepared regulations since May 2019. [42]