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The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. [1]
Vinca (/ ˈ v ɪ ŋ k ə /; [2] Latin: vincire "to bind, fetter") is an Old World genus of flowering plants in the family Apocynaceae, The English name periwinkle is shared with the related genus Catharanthus (and with the mollusc Littorina littorea). Some Vinca species are cultivated but have also spread invasively.
Vindesine, also termed Eldisine, is a semisynthetic vinca alkaloid derived from the flowering plant Catharanthus roseus. [1] Like the natural (e.g. vinblastine and vincristine) and semisynthetic vinca alkaloids (e.g. vinorelbine and vinflunine) derived from this plant, vindesine is an inhibitor of mitosis that is used as a chemotherapy drug. [2]
Vinpocetine (ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine, differing by the removal of a hydroxyl group and by being the ethyl rather than the methyl ester of the underlying carboxylic acid. Vincamine is extracted from either the seeds of Voacanga africana or the leaves of Vinca minor (lesser periwinkle).
The Message is a reading Bible translated from the original Greek and Hebrew scriptures and it has been reviewed and approved by 20 biblical scholars, according to The Message website ...
Vincaminol (C 20 H 26 N 2 O 2) is a chemical that is a part of the Vinca alkaloid group, which were discovered in the 1950s and are derived from Vinca minor (periwinkle). [1] [2] Vincaminol is not as well known as some of the other Vinca alkaloids such as vinblastine, vinorelbine, vincristine, and vindesine, which are the most medically useful Vinca alkaloids.
The first individual alkaloid, morphine, was isolated in 1804 from the opium poppy (Papaver somniferum). [1] Alkaloids are a broad class of naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. [2]