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In hormone therapy, trans women often experience slight weight gain as men generally carry higher levels of visceral fat compared to subcutaneous fat, and less fat overall compared to women. Over months and years, HRT causes the body to accumulate new fat in a feminine pattern ( gynoid fat ).
Proceptivity and receptivity in the female rat are indicators of sexual motivation, thus indicating a direct relationship between estrogen levels and sexual motivation. In addition, female rats receiving doses of estrogen and progesterone were more likely to exert effort at gaining sexual attention from a male rat. [17]
[275] [276] However, the available evidence overall does not support the use of estradiol and other estrogens for improving sexual desire and function in women as of 2016. [276] An exception is the use of estrogens to treat vaginal atrophy. [276] Estrogen therapy has been proposed as a potential treatment for autism but clinical studies are ...
Estrogen plus other progestogens <5 years ≥5 years: 1.70 (1.50–1.91) 2.02 (1.81–2.26) Footnotes: a = Oral estrogen plus progesterone was not analyzed because there was a low number of women who used this therapy. Sources: See template.
Christine Derzko stated that the evidence supported the use of bioidentical estrogen plus progesterone, but since the trial was an observational cohort study rather than a randomized controlled trial that compared different types of hormones head-to-head, more data was required before concluding bioidentical hormones were safer and preferred ...
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