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Detomidine is an imidazole derivative and α 2-adrenergic agonist, [1] used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride . It is a prescription medication available to veterinarians sold under various trade names.
It is also commonly paired with sedatives, such as xylazine and detomidine, to make the horse easier to handle during veterinary procedures. Side effects specific to horses include sedation and CNS excitement (displayed by head pressing or tossing). Overdosing may result in seizures, falling, salivation, constipation, and muscle twitching.
Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt.In the United States, it is regulated by the U.S. Food and Drug Administration (FDA), and may only be lawfully distributed by order of a licensed veterinarian.
The nascent Horseracing Integrity and Safety Authority on Thursday released a draft of proposed anti-doping and medication control rules designed to bring uniformity to a sport that has operated ...
Dexmedetomidine may be useful for the treatment of the negative cardiovascular effects of acute amphetamines and cocaine intoxication and overdose. [27] [28] Dexmedetomidine has also been used as an adjunct to neuroaxial anesthesia for lower limb procedures. [29] It has been successfully used to treat opioid withdrawal symptoms. [30]
Rep. Nancy Pelosi underwent a “successful” hip replacement surgery Saturday and is “well on the mend,” according to a spokesperson, one day after being hospitalized from an injury ...
Customers who purchased Deep River brand potato chips labeled “Non-GMO Ingredients” may be eligible for a cash payment from a class action settlement.
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
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