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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
On average obese people have a greater energy expenditure than normal weight or thin people and actually have higher basal metabolic rates. [45] [46] This is because it takes more energy to maintain an increased body mass. [47] Obese people also underreport how much food they consume compared to those of normal weight. [48]
When energy intake exceeds energy expenditure (when the body is in positive energy balance), the body can store the excess energy as fat. However, the physiology of weight gain and loss is complex involving numerous hormones, body systems and environmental factors. Other factors besides energy balance that may contribute to gaining weight include:
Set point theory can be construed as implying weight regulation in a wide or tight range around the set point, in a symmetric or in an asymmetric manner (i.e. treating weight gain and loss either the same or differently), and may apply to regulation of body fat levels specifically (in a multi-compartment model) or to overall body weight.
Older twin studies suggest that 79 percent to 93 percent of the risk of bipolar disorder is genetic. ... medications include weight gain and fatigue or drowsiness. These side effects can usually ...
Nutritional genomics, also known as nutrigenomics, is a science studying the relationship between human genome, human nutrition and health. People in the field work toward developing an understanding of how the whole body responds to a food via systems biology, as well as single gene/single food compound relationships.
When energy balance is highly negative (meaning the woman is starving) or energy flux is very high (meaning the woman is exercising at extreme levels, but still consuming enough calories), the ovarian cycle stops and females stop menstruating. Only if a female has an extremely low body fat percentage does energy status affect menstruation.
Sudden weight gain can be an early symptom of heart failure, according to the American Heart Association. Weight gain of more than two or three pounds within a 24 hour period may be a sign your ...