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Zaleplon, sold under the brand name Sonata among others, is a sedative and hypnotic which is used to treat insomnia. It is a nonbenzodiazepine or Z-drug of the pyrazolopyrimidine class. [ 10 ] It was developed by King Pharmaceuticals and approved for medical use in the United States in 1999.
The 2023 Beers criteria lists all three Z-drugs approved in the US (zolpidem, zaleplon, eszolpiclon) as unsuitable for older people. [40] The Z-drug zaleplon may have fewer side effects compared to benzodiazepines. [41] Much like benzodiazepines, Z-drugs are associated with an increased incidence of dementia.
Zaleplon (Sonata), with a 4-hour restriction on subsequent flight operation; Zolpidem (Ambien), with a 6-hour restriction on subsequent flight operation; Go pill
Like zaleplon, zolpidem may increase slow-wave sleep but cause no effect on stage 2 sleep. [ 59 ] A 2004 meta-analysis compared benzodiazepines against nonbenzodiazepines and showed few consistent differences between zolpidem and benzodiazepines in terms of sleep onset latency , total sleep duration, number of awakenings, quality of sleep ...
This multi-page article lists pharmaceutical drugs alphabetically by name. Many drugs have more than one name and, therefore, the same drug may be listed more than once. ...
In 2015, the American Geriatrics Society reviewed the safety information about eszopiclone and similar drugs and concluded that the "nonbenzodiazepine, benzodiazepine receptor agonist hypnotics (eszopiclone, zaleplon, zolpidem) are to be avoided without consideration of duration of use because of their association with harms balanced with their ...
Nonbenzodiazepines such as zaleplon and zolpidem and low doses of sedating antidepressants are sometimes used as alternatives to benzodiazepines. [95] [96] Long-term use of benzodiazepines is associated with increased risk of cognitive impairment and dementia, and reduction in prescribing levels is likely to reduce dementia risk. [13]
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Zaleplon. PubMed provides review articles from the past five years (limit to free review articles)