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Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Lidocaine's half-life in the body is about 1.5–2 hours. [2] The time it takes for the anesthetic medication to prevent pain in the area (speed of onset) and length of time that the area does not have painful sensations are considerations when choosing an appropriate approach to dental treatment.
MDCalc is a free online medical reference for healthcare professionals that provides point-of-care clinical decision-support tools, including medical calculators, scoring systems, and algorithms. [1]
The tool can also determine how much money you'll have when your time comes. Researchers analyzed aspects of a person’s life story between 2008 and 2016, with the model seeking patterns in the data.
The wait time and isolation of blood flow from the region is important for avoiding an overdose of the anesthetic agent in the blood which can lead to hypotension, convulsions, arrhythmia, and death. Cardiotoxic local anesthetic agents like bupivacaine and etidocaine are strictly contraindicated .
In medicine, specifically in end-of-life care, palliative sedation (also known as terminal sedation, continuous deep sedation, or sedation for intractable distress of a dying patient) is the palliative practice of relieving distress in a terminally ill person in the last hours or days of a dying person's life, usually by means of a continuous intravenous or subcutaneous infusion of a sedative ...
Without special treatment after circulation is restarted, full recovery of the brain after more than 3 minutes of clinical death at normal body temperature is rare. [6] [7] Usually brain damage or later brain death results after longer intervals of clinical death even if the heart is restarted and blood circulation is successfully restored ...
Changes to a body occurring after death (post-mortem changes) include: [3] Algor mortis: body cooling; Livor mortis: settling of blood in the lowest-placed parts of the body; Rigor mortis: stiffening of limbs. Conditions at the scene of death affect the estimation of time of death.