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The drug was quickly adopted as the first widely effective anti-convulsant, though World War I delayed its introduction in the U.S. [48] In 1939, a German family asked Adolf Hitler to have their disabled son killed; the five-month-old boy was given a lethal dose of Luminal after Hitler sent his own doctor to examine him.
The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs. The DDD enables comparison of drug usage between different drugs in ...
The therapeutic ratio in radiotherapy for cancer treatment is determined by the maximum radiation dose for killing cancer cells and the minimum radiation dose causing acute or late morbidity in cells of normal tissues. [13] Both of these parameters have sigmoidal dose–response curves. Thus, a favorable outcome in dose–response for tumor ...
In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. If multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that should be broken up ...
Nifuroxazide is an oral nitrofuran antibiotic, patented since 1966 [1] and used to treat colitis and diarrhea in humans and non-humans. [2] It is sold under the brand names Ambatrol, Antinal, Bacifurane, Diafuryl (Turkey), Benol (Pakistan), Pérabacticel (France), Antinal, Diax (Egypt), Nifrozid, Ercefuryl (Romania, Czech Republic, Russia), Erfuzide (Thailand), Endiex (Slovakia), Enterofuryl ...
Similar findings have been reported for colorectal cancer as well. [22] [23] There are two types of circulating tumor cell cluster, one that consists of cancer cells only is termed homotypic. A CTC cluster that also incorporates other cells including white blood cells, fibroblasts, endothelial cells, and platelets, is termed heterotypic. [24]
World map of infant mortality rates in 2017. Infant mortality is the death of an infant before the infant's first birthday. [1] The occurrence of infant mortality in a population can be described by the infant mortality rate (IMR), which is the number of deaths of infants under one year of age per 1,000 live births. [1]
True photographic memory (the ability to remember endless images, particularly pages or numbers, with such a high degree of precision that the image mimics a photo) has never been demonstrated to exist in any individual, [462] although a small number of young children have eidetic memory, where they can recall an object with high precision for ...