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Using PREVENT to calculate the 10-year risk for developing heart disease, the researchers determined that some 40% fewer people would have met the criteria for a statin prescription.
Over 17 million people may be taking statins they do not need To investigate how PREVENT works, the scientists took data from the National Health and Nutrition Examination Survey from January 2017 ...
The Framingham Risk Score is a sex-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. The Framingham Risk Score was first developed based on data obtained from the Framingham Heart Study, to estimate the 10-year risk of developing coronary heart disease. [1]
The findings show a decrease in mortality among people 60 years of age and older — including people over the age of 85 — who took statins. ... and 85% for people over 80. For people ages 40 to ...
The NNT is the average number of patients who need to be treated to prevent one additional bad outcome. It is defined as the inverse of the absolute risk reduction , and computed as 1 / ( I u − I e ) {\displaystyle 1/(I_{u}-I_{e})} , where I u {\displaystyle I_{u}} is the incidence in the control (unexposed) group, and I e {\displaystyle I_{e ...
JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).
HDL cholesterol: above 40 mg/dL (for men) and above 50 mg/dL (for women) Triglycerides: below 150 mg/dL While all your levels are important, your doctor will likely focus on your LDL cholesterol ...
The Scandinavian Simvastatin Survival Study (also known as the 4S study), was a multicentre, randomized, double-blind, placebo-controlled clinical trial, which provided the initial data that supported the use of the cholesterol-lowering drug, simvastatin, in people with a moderately raised cholesterol and coronary heart disease (CHD); that is people who had previously had a heart attack or angina.