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Another important cell type is the pulmonary neuroendocrine cell. These are innervated cells that only make up around 0.5% of the respiratory epithelial cells. [7] The ciliated cells are columnar epithelial cells with specialized ciliary modifications. The ciliated cells make up between 50 and 80 per cent of the epithelium. [8]
Club cells, also known as bronchiolar exocrine cells, [1] are low columnar/cuboidal cells with short microvilli, found in the small airways (bronchioles) of the lungs. [2] They were formerly known as Clara cells. Club cells are found in the ciliated simple epithelium. These cells may secrete glycosaminoglycans to protect the bronchiole lining ...
The two types of cell are known as type I and type II cells [32] (also known as pneumocytes). [3] Types I and II make up the walls and alveolar septa. Type I cells provide 95% of the surface area of each alveoli and are flat ("squamous"), and Type II cells generally cluster in the corners of the alveoli and have a cuboidal shape. [33]
The Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types in the human body". [13] By 2018, the Human Cell Atlas description based the project on the assumption that "our characterization of the hundreds of types and subtypes of cells in the ...
The lungs which are located in the thoracic cavity, are protected from physical damage by the rib cage. At the base of the lungs is a sheet of skeletal muscle called the diaphragm. The diaphragm separates the lungs from the stomach and intestines.
There are three major types of alveolar cell. Two types are pneumocytes or pneumonocytes known as type I and type II cells found in the alveolar wall, and a large phagocytic cell known as an alveolar macrophage that moves about in the lumens of the alveoli, and in the connective tissue between them. Type I cells, also called type I pneumocytes ...
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The respiratory airway secretory cell (RAS), is found in the lungs of humans and some other mammals, notably ferrets. They are facultative progenitors that have important functional roles in maintaining lung airway health. Their role in maintaining the gas-exchange compartment of the lung is critical and they may be altered in chronic lung disease.