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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.
Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has been identified. [ 5 ]
16p11.2 deletion syndrome is a rare genetic condition caused by microdeletion on the short arm of chromosome 16. Most affected individuals experience global developmental delay and intellectual disability, as well as childhood-onset obesity. [1] 16p11.2 deletion is estimated to account for approximately 1% of autism spectrum disorder cases. [3] [4]
For the first time in over a decade, obesity rates in the United States may finally be heading in the right direction and new weight loss drugs like semaglutide could be part of the reason why. A ...
233107 Ensembl ENSG00000153885 ENSMUSG00000030499 UniProt Q96SI1 Q8K0E1 RefSeq (mRNA) NM_001129994 NM_001129995 NM_024076 NM_146188 NM_001360818 NM_001360820 RefSeq (protein) NP_001123466 NP_001123467 NP_076981 NP_666300 NP_001347747 NP_001347749 Location (UCSC) Chr 19: 33.8 – 33.82 Mb Chr 7: 34.34 – 34.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Potassium channel ...
Obesity risk factors can be genetic or environmental — the latter has to do with lifestyle choices and things you don’t have as much control over, like illness or work stress.
The obesity rate among U.S. adults fell in 2023 for the first time in over a decade, according to a new study released on Friday. The study published in the journal JAMA Health Forum found that ...
Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and represents just under 3% of the total DNA in cells .