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  2. Seasonal affective disorder - Wikipedia

    en.wikipedia.org/wiki/Seasonal_affective_disorder

    Modafinil may be an effective and well-tolerated treatment in patients with seasonal affective disorder/winter depression. [49] Another explanation is that vitamin D levels are too low when people do not get enough Ultraviolet-B on their skin. An alternative to using bright lights is to take vitamin D supplements.

  3. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The main limitation for the monoamine hypothesis of depression is the therapeutic lag between initiation of antidepressant treatment and perceived improvement of symptoms. One explanation for this therapeutic lag is that the initial increase in synaptic serotonin is only temporary, as firing of serotonergic neurons in the dorsal raphe adapt via ...

  4. Management of depression - Wikipedia

    en.wikipedia.org/wiki/Management_of_depression

    In a meta-analysis of 16 studies and 4,356 patients, the average improvement in depressive symptoms was an effect size of d = 0.63 (95% CI, 0.36 to 0.90). [38] IPT combined with pharmacotherapy was more effective in preventing relapse than pharmacotherapy alone, number needed to treat = 7.63. [38]

  5. What's the Connection Between Weight & Depression? - AOL

    www.aol.com/whats-connection-between-weight...

    Emotionally, depression can take a major toll, making you feel sad, irritable, helpless or fatigued, among other symptoms. It can also manifest physically, causing aches and pains, headaches and ...

  6. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    Clinical trials of vitamin D supplementation for depressive symptoms have generally been of low quality and show no overall effect, although subgroup analysis showed supplementation for participants with clinically significant depressive symptoms or depressive disorder had a moderate effect. [149]

  7. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    There is limited evidence that vitamin D supplementation is of value in alleviating the symptoms of depression in individuals who are vitamin D-deficient. [102] Lithium appears effective at lowering the risk of suicide in those with bipolar disorder and unipolar depression to nearly the same levels as the general population. [218]

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