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1,2-Dibromobenzene: 1,3-Dibromobenzene [1] 1,4-Dibromobenzene [2] [3] [4] Structure Molecular formula: C 6 H 4 Br 2: Molar mass: 235.906 g/mol Appearance colorless liquid colorless liquid white solid CAS number [583-53-9] [108-36-1] [106-37-6] Properties Density and phase: 1.9940 g/ml, liquid 1.9523 g/ml, liquid 1.84 g/ml, solid Solubility in ...
1,3-Dibromobenzene has been used as a starting material in the synthesis of antiviral Lufotrelvir, in human clinical trials for the treatment of COVID-19. [3] The first step is formylation of 1,3-dibromobenzene to 2,6-dibromobenzaldehyde, by lithiation with lithium diisopropylamide in THF , followed by quenching with dimethylformamide .
1-Bromo-3-chlorobenzene: by (3-chlorophenyl)trimethylgermanium by electrophilic substitution [2] [better source needed] 1-Bromo-4-chlorobenzene: From a derivative of (4-bromophenyl)silane using N-bromosuccinimide [3] From 4-chlorophenol using triphenylphosphine dibromide [4] or phenylphosphorus tetrachloride [5]
[3] Bromobenzene is used to introduce a phenyl group into other compounds. One method involves its conversion to the Grignard reagent, phenylmagnesium bromide. This reagent can be used, e.g. in the reaction with carbon dioxide to prepare benzoic acid. [4] Other methods involve palladium-catalyzed coupling reactions, such as the Suzuki reaction.
Chemical structure of 2-bromophenol. A bromophenol is an organic compound consisting of hydroxyl groups and bromine atoms bonded to a benzene ring. They may be viewed as hydroxyl derivatives of bromobenzene, or as brominated derivatives of phenol.
Bromoform was discovered in 1832 by Löwig who distilled a mixture of bromal and potassium hydroxide, as analogous to preparation of chloroform from chloral. [5]Bromoform can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating chloroform with aluminium bromide.
3,4-Dibromophenol, 1,2-Dibromo-4-hydroxybenzene 3,5-Dibromophenol, 1,3-Dibromo-5-hydroxybenzene Structural formula: CAS Number: 57383-80-9: 615-58-7: 28165-52-8: 608-33-3: 615-56-5: 626-41-5 PubChem: CID 34264 from PubChem: CID 12005 from PubChem: CID 34177 from PubChem: CID 11847 from PubChem: CID 12003 from PubChem: CID 12280 from PubChem ...
1,2-Dibromobenzene (o-dibromobenzene) is an aryl bromide and isomer of dibromobenzene. It is one of three isomers, the others being 1,3- and 1,4-dibromobenzene. It is a colorless liquid, although impure samples appear yellowish. The compound is a precursor to many 1,2-disubstituted derivatives of benzene.