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Just in time for fall and winter sniffles, an advisory committee to the US Food and Drug Administration has decided that a popular ingredient in oral cold and allergy medications doesn’t work.
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
In adults and children age 2 and older, use it only on the neck and chest to ease coughing during a cold, per the Mayo Clinic. Vicks VapoRub is made of ingredients such as camphor, eucalyptus oil ...
These include for adults: antihistamines, antihistamine-decongestant combinations, benzonatate, anti asthmatic-expectorant-mucolytic combinations, expectorant-bronchodilator combinations, leukotriene inhibitors, ambroxol, and guaifenesin, sometimes with analgesics, antipyretics, anti inflammatories, and anticholinergics; and for children ...
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
Topical decongestants are decongestants applied directly to the nasal cavity. Their effectiveness by themselves in the common cold appears to have a small benefit in adults. [1] Topical decongestants should only be used by patients for a maximum of 5–7 days in a row, because rebound congestion may occur in the form of rhinitis medicamentosa ...
The FDA announced a proposal to remove oral phenylephrine, found in many popular OTC decongestants, from shelves. The reason for the ban is that the ingredient just isn’t effective, the FDA says.
It binds to α 1 and α 2 adrenergic receptors [11] in the nasal mucosa. Due to its sympathomimetic effects, it should not be used by people with high blood pressure , or other heart problems. Extended usage of xylometazoline can result in decreased effectiveness or a buildup of tolerance against the drug. [ 12 ]