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In survival analysis, the hazard ratio (HR) is the ratio of the hazard rates corresponding to the conditions characterised by two distinct levels of a treatment variable of interest. For example, in a clinical study of a drug, the treated population may die at twice the rate of the control population.
The hazard ratio is the quantity (), which is = in the above example. From the last calculation above, an interpretation of this is as the ratio of hazards between two "subjects" that have their variables differ by one unit: if P i = P j + 1 {\displaystyle P_{i}=P_{j}+1} , then exp ( β 1 ( P i − P j ) = exp ( β 1 ( 1 ...
This approach performs well for certain measures and can approximate arbitrary hazard functions relatively well, while not imposing stringent computational requirements. [5] When the covariates are omitted from the analysis, the maximum likelihood boils down to the Kaplan-Meier estimator of the survivor function.
The 'bathtub curve' hazard function (blue, upper solid line) is a combination of a decreasing hazard of early failure (red dotted line) and an increasing hazard of wear-out failure (yellow dotted line), plus some constant hazard of random failure (green, lower solid line). The bathtub curve is a particular shape of a failure rate graph.
In full generality, the accelerated failure time model can be specified as [2] (|) = ()where denotes the joint effect of covariates, typically = ([+ +]). (Specifying the regression coefficients with a negative sign implies that high values of the covariates increase the survival time, but this is merely a sign convention; without a negative sign, they increase the hazard.)
In two-sector macroeconomic models, the Harrod–Johnson diagram, occasionally referred to as the Samuelson-Harrod-Johnson diagram, is a way of visualizing the relationship between the output price ratios, the input price ratios, and the endowment ratio of the two goods. [1] [2] Often the goods are a consumption and investment good, and this ...
The inverse Mills ratio is the ratio of the probability density function to the complementary cumulative distribution function of a distribution. Its use is often motivated by the following property of the truncated normal distribution. If X is a random variable having a normal distribution with mean μ and variance σ 2, then
A vulnerability index is a measure of the exposure of a population to some hazard. Typically, the index is a composite of multiple quantitative indicators that via some formula, delivers a single numerical result. Through such an index "diverse issues can be combined into a standardised framework...making comparisons possible". [1]