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A mastoidectomy is a procedure performed to remove the mastoid air cells [1] near the middle ear. The procedure is part of the treatment for mastoiditis, chronic suppurative otitis media or cholesteatoma. [2] Additionally, it is sometimes performed as part of other procedures, such as cochlear implants, [3] or to access the middle ear.
Mastoiditis is the result of an infection that extends to the air cells of the skull behind the ear. Specifically, it is an inflammation of the mucosal lining of the mastoid antrum and mastoid air cell system inside [1] the mastoid process. The mastoid process is the portion of the temporal bone of the skull that is behind
The cells receive arterial supply from the stylomastoid branch of the occipital artery or posterior auricular artery, and (sometimes) a mastoid branch of the occipital artery. [1]: 749 The superior petrosal sinus receives venous drainage from the mastoid air cells (mastoid infection may thus lead to a cerebellar abscess). [2]: 443
This recess is a possible route of spread of infection to the mastoid air cells located in the mastoid process of the temporal bone of the skull. Inflammation which has spread to the mastoid air cells is very difficult to drain and causes considerable pain.
Mast cell activation syndrome (MCAS) is a term referring to one of two types of mast cell activation disorder (MCAD); the other type is idiopathic MCAD. [1] MCAS is an immunological condition in which mast cells, a type of white blood cell, inappropriately and excessively release chemical mediators, such as histamine, resulting in a range of chronic symptoms, sometimes including anaphylaxis or ...
The mastoid antrum (tympanic antrum, antrum mastoideum, Valsalva's antrum) is an air space in the petrous portion of the temporal bone, communicating posteriorly with the mastoid cells and anteriorly with the epitympanic recess of the middle ear via the aditus to mastoid antrum (entrance to the mastoid antrum). These air spaces function as ...
Mast cell stabilizers are medications used to prevent or treat certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the ...
The walls of the antrum are lined by mucosa which is continuous with that lining the mastoid cells and tympanic cavity. [3] The medial wall of the aditus features a ridge created by the underlying facial canal, and a bulge created by the underlying ampulla of the lateral semicircular canal.