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The Dengvaxia controversy (locally [dɛŋˈvakʃa]) occurred in the Philippines when the dengue vaccine Dengvaxia was found to increase the risk of disease severity for some people who had received it. [1] [2] A vaccination program run by the Philippine Department of Health (DOH) administered Sanofi Pasteur's Dengvaxia to schoolchildren. [3]
Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue (formerly called dengue hemorrhagic fever or dengue shock syndrome). [21] [23] Severe dengue can lead to shock, internal bleeding, organ failure and even death. [24]
In August 2019, the Philippines declared an epidemic after more than 622 people had died of the disease in that country. [1] [14] The Philippines Department of Health reported that there were over 146,000 dengue fever cases from the beginning of 2019 to 20 July, which was "a 98% increase from the same time period last year". [14]
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
A record surge in dengue cases throughout Latin America and the Caribbean this year prompted the head of the Pan American Health Organization to call for collective action to curb the deadly ...
Reported cases of dengue in the Americas nearly tripled to a record high of over 12.6 million this year, including 21,000 severe cases and over 7,700 deaths, the Pan American Health Organization ...
South America is seeing a surge in cases of the mosquito-borne disease dengue during the southern hemisphere summer, prompting Brazil to roll out a novel vaccine campaign, while in Argentina many ...
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]